Cambridge Paternity Test Centers - Maryland

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Rapid Screenings - STD - HIV - DNA Testing
(866) 867-0393
508 Maryland Ave Ste 2, Cambridge, MD 21613
Featured Article

Methods Of Prenatal Genetic Testing

by: Rich Fuller

Prenatal genetic testing is used for many reasons, in particular paternity testing and testing for genetic disorders, but how is this done? Prenatal genetic testing is done primarily using two methods, namely amniocentesis and CVS.

Amniocentesis involves taking a sample of the amniotic fluid which surrounds the unborn fetus and testing the DNA found in this fluid. The amniotic fluid includes cells which are shed from the body of the unborn baby naturally as it grows. These cells contain the baby's DNA and so can be used to test for genetic disorders in the baby or to compare it to an alleged father's DNA to discover if the father really is the father of the child. Prenatal genetic testing using amniocentesis is generally done during the second trimester of the pregnancy or after 12 weeks.

The second method used in prenatal genetic testing is CVS or chorionic villi sampling. This is normally done between 10 and 12 weeks in the first trimester of the pregnancy and involves taking a small piece of the placenta which includes chorionic villi to be tested. This contains cells of the baby and so can be used as a sample of the baby's DNA to test for paternity or certain genetic disorders.

Both of these methods of prenatal genetic testing have certain risks. The rate of problems involved may be relatively small but it is necessary for each mother or family unit to consider the risks involved and decide whether they want to get the prenatal genetic testing done and decide with their doctor what method they are going to use. The risk of a serious complication or miscarriage in both cases is generally between 0.5 and 1%.

In conclusion the two main methods used in prenatal genetic testing are amniocentesis and CVS. Amniocentesis involves taking a sampling of the amniotic fluid surrounding an unborn fetus in the second trimester, while CVS includes taking a portion of the placenta in the first trimester of pregnancy. Both these methods of prenatal genetic testing have their inherent risks and these should be considered when deciding to have prenatal genetic testing done or which method to use.

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